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The Ultimates!
While it's true that Binder, Plasmoid, Blackstar, Slick, and Charger offer varying degrees of well-roundedness, lameness, and complexity in build -- I think that when they worked together as a team, they were pretty devastating.
Binder (with his various glue gun attacks), along with Slick (and his friction-reduction attacks) tended to hamstring the heavy hitters of the hero team. With their mobility, they can stay out of reach while their teammates run interference and take out the immobilised heroes.
There's a pretty tough physical attacker in Blackstar, a pretty dangerous ranged attacker in Charger, and a devastating area effect / energy projector in Plasmoid.
If the Ultimates have their teamwork down, they have a rough fight ahead of them.