Following up my last post, here's a list of some of the games I'd be interested in running:
No surprise there, I've posted a lot on the attraction of this kitchen sink setting.
It also allows me a fair amount of latitude in terms of the types of game sessions I can run, and gives me any number of excuses to take away high technology away from the players when I need to have the isolated, out of touch, and without any wonderful tech devices.
It also grants some rationale for a Science Fantasy campaign where swords and guns can be used.
D&D (of some kind)
It'd be one part exploration of dungeons, one part exploration of the world, and one part killing monsters. I wouldn't really take it too much in the direction of a city-based adventure, as my knowledge of medieval technology and life is somewhat challenged; I would do what I feel D&D excels at: helping players -- through their PCs -- explore the unknown, kill the nasty monsters that inhabit it, and claim the best of that dark wilderness (below or above ground) for their own.
Like the campaign that inspired it, I'd have players make two characters -- one for the ground forces and one for the space-based battles -- and let the discoveries and progress of the campaign unfold from those two vantage points.
For ship-to-ship combat, I might use the rules for Starmada: Admiralty Edition.
Mutants & Masterminds 3rd Edition / DC Adventures
If there were some like-minded Hero players, I'd run Champions though.
Or give alternative supers rule systems like Icons or G-Core a try. I think BASH! is another system I'd take a look at, although the classics like Mayfair's DC Heroes and the TSR Marvel Super-Heroes RPG would also spark my interest.